**Selected for Doody’s Core Titles® 2024 in Pharmacology** Lehne's Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants, 2nd Edition builds on the same foundation of clearly explained, up-to-date, and clinically current content as the trusted Lehne undergraduate text, while focusing on the information that advanced practice nurses and Physician Assistants specifically need for safe and effective prescribing. Three introductory chapters provide foundational content for new prescribers in the areas of prescriptive authority, rational drug selection, prescription writing, and promoting positive outcomes of drug therapy. Core drug chapters are focused on the drugs that prescribers will most commonly see in clinical practice. A sharp focus is also placed on pharmacotherapeutic decision-making, with Black Box Warnings and new bulleted Key Prescribing Considerations features. The second edition features completely new chapters on Genetic and Genomic Considerations, Muscarinic Antagonists and Immunomodulators, and updated content throughout. It’s everything advanced practice nursing and Physician Assistant students need to be safe and effective prescribers!