This unique guide addresses the state of the art of optical system design for biomedical applications. It focuses on the latest systems and lenses, moving from the characteristics of entire optical systems to explain the optical configurations used for different applications, requirements for the imaging lenses, and the design of various systems, including biomedical imaging systems not covered in any other text. Readers will find useful examples of optical system design plus real-world advice on how to develop more effective imaging systems for biomedical, display, and digital imaging applications.