Hailed by JAMA as "the best single-volume text on the subject," this classic is now in its thoroughly updated, expanded Third Edition. In 136 chapters written by more than 150 expert contributors, the book provides encyclopedic coverage of the history, causes, prevention, and treatment of environmental and occupational diseases.The Third Edition features new chapters on molecular carcinogenesis, biological markers, genetic susceptibility to environmentally-induced diseases, and molecular mechanisms of asthma and particle-induced lung disease. Full consideration is given to recently recognized occupational diseases and hazards such as occupational tuberculosis, toxic liver disorders and endocrine disruptions, multiple chemical sensitivities, carpal tunnel syndrome, hazards of the petroleum refining industry, sleep disorders, and sick building syndrome. Environmental concerns addressed include acid rain, PCBs in aquatic environments, and Persian Gulf War health issues. This edition also includes chapters on low back pain, biomechanics, respirators, and managed care and occupational health.