Juan de Ávila (1499-1569) was one of the most significant exponents of Spanish Golden Age spirituality. His work throughout Andalusia gave rise to the school of Avilista spirituality, a spirituality adopted by both lay men and women as well as secular and regular members of the clergy who were inspired by his stress on moral and spiritual formation and were bound together by the observance of a rigorous program of spiritual discipline. Scholars have increasingly identified him as the author of a distinctively judeoconverso spirituality. Currently, however, there are no comprehensive studies of his spirituality that seriously take into account his judeoconverso background. The present work seeks to analyze his ascetic spirituality and place it against its proper early-modern Spanish context.