In today’s networked economy, each organization is more and more shaped by the system of its long-term business interactions. Innovation processes cannot be successfully designed and managed unless the complex influences of business networking on innovation processes and innovation-related performances are clearly understood. But extant theories on business networks are fragmented, and each of them, taken singularly, provides only partial or poor understanding of the impacts of business networking on innovation performances. Based on qualitative research on three exemplary worst practices and on expert panel discussion and validation, Francesca Ricciardi develops novel quantitative models in this theory-building work to explain innovation performances in different interorganizational networks.