This book features research papers presented at the 4th International Conference on Intelligent Sustainable Systems (ICISS 2021), held at SCAD College of Engineering and Technology, Tirunelveli, Tamil Nadu, India, during February 26–27, 2021. The book discusses the latest research works that discuss the tools, methodologies, practices, and applications of sustainable systems and computational intelligence methodologies. The book is beneficial for readers from both academia and industry.