This reference book provides a comprehensive overview of models and therapeutic approaches against neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and Amyotrophic lateral sclerosis. It explores models based on the chemical, induced, cellular, genetic, transgenic, 3D organoids in neurodegenerative diseases. The book also reviews advantages and limitations of these models in designing the treatment strategies. Additionally, the book covers the emerging field of bioinformatics and its application in modelling various neurodegenerative diseases. Towards the end, the book highlights the role of holistic management, precision medicine, OMICS, and gene therapy against neurodegenerative disorders. It examines the implications and significance of stem cells therapy in translational models of neurodegenerative diseases This book is an invaluable resource for researchers, neuroscientists, and neurosurgeons for getting in-depth information on the neurodegenerative models and therapeutic approaches.

Key Features:

Provides comprehensive overview of neurodegenerative diseases and their models.

Examines the limitations associated with modelling neurodegenerative diseases.

Presents novel treatment strategies for Alzheimer's disease using cellular models.

Reviews importance of 3D organoid models for therapeutic approaches in Parkinson's disease.

Covers modeling techniques in understanding prion diseases.

Explores the role of genetic models in understanding Huntington's disease.