Modern culture has found itself on drugs. Beyond their psychoactive effects, they have shaped some of the modern era's most fundamental philosophies and even helped expose the neurochemistry of the human brain. This examination of writing on drugs, including Coleridge on opium, Michaux on mescaline, Freud on cocaine and Burroughs on everything, is an exploration of the profound and pervasive influence of drugs on contemporary and historical culture. The author argues that drugs have been integral to modern politics, media and technology.