Protein biochips are widely recognized as critical tools for achieving a more global, integrated understanding of biology and human disease.
The book takes an interdisciplinary approach by integrating elements of materials science, chemistry, protein engineering, and physics in a non-technical manner. It begins with an introduction to the field, chip design and development, and assays. The author then delves into problems addressed by protein biochips, including: disease biomarker applications, early tumor risk assessment, screening for drug discovery, and clinical trial design. The book concludes with a discussion of future directions.
Key features:
· Provides a comprehensive yet approachable reference for the field
· Offers a practical guide to how protein biochips are designed, built, and applied to various problems in biology and medicine
· Accessible to tool developers and end users involved in drug development, clinical diagnosis, and medical research
· Discusses multitarget screening, protein profiling, large-scale protein arrays, and multiplexing
· Covers the range of applications in basic and clinical research
· Well illustrated with numerous diagrams, tables, schemes, microarray images, and photomicrographs
· Boxes highlight key processes and protocols
· Includes contributions from luminaries who offer a unique and personal view on various key topics
· Written by a pioneer in the field