This unique volume in our Drugs and Pharmaceutical Sciences series covers the development of gene therapy today, the technology involved, clinical applications of siRNA, non-viral vector-based mRNA delivery using nanotechnology, and RNA based vaccines for treating the infectious diseases. It also presents the current application of the CRISPR/Cas9 gene-editing technique which has revolutionized genome editing and which was awarded the 2020 Nobel Prize in Chemistry. Several new drug delivery systems are explored for the applications of gene therapy. These are found to be useful in treating chronic illnesses, including cancer and infectious diseases.

Key Features:






Overview of the development of gene therapy



Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing



Presents CRISPR gene therapy recent trends and applications



Discusses siRNA, mRNA, and DNA plasmids