In vain did Marie de Medicis represent the injury which Louis must, by such an enterprise, inflict upon his sister; the project flattered the vanity of the King, and accordingly on the 14th of May the vanguard of the French army entered the Duchy, and before the middle of the ensuing month the whole of Savoy, with the exception of Montmelian, was in the possession of his troops. This puny triumph was, however, counterbalanced and outweighed by the disasters at Casal and Mantua, the former of which, from the failure of provisions and reinforcements, fell into the hands of Spinola; while the latter, after having had twenty-five thousand of its inhabitants carried off by the plague, was ultimately lost through treason, and delivered over to pillage by the Imperialist generals.