In Copernicus in the Cultural Debates of the Renaissance, Pietro Daniel Omodeo presents a general overview of the reception of Copernicus’s astronomical proposal from the years immediately preceding the publication of De revolutionibus (1543) to the Roman prohibition of heliocentric hypotheses in 1616. Relying on a detailed investigation of early modern sources, the author systematically examines a series of issues ranging from computation to epistemology, natural philosophy, theology and ethics. In addition to offering a pluralistic and interdisciplinary perspective on post-Copernican astronomy, the study goes beyond purely cosmological and geometrical issues and engages in a wide-ranging discussion of how Copernicus’s legacy interacted with European culture and how his image and theories evolved as a result.