This volume addresses the issue of freedom in the philosophy of Deleuze and Guattari. This is all the more challenging in that Deleuze-Guattari almost never use the term freedom, preferring instead, the concept of the refrain. The essays collected in the volume show that freedom has been understood in a remarkably narrow sense and that in fact freedom operates as the refrain in every realm of thought and creation. The motivating approach in these essays is Deleuze-Guattari’s emphasis on the irreality of media and capitalistic sign regimes, which they perceive to have taken over even the practices of philosophy, the arts, and science. By offering a clear and engaging treatment of the underexplored issue of freedom, this volume moves the discussion of Deleuze-Guattari’s philosophy forward in ways that will appeal to researchers in Continental philosophy and a wide range of other disciplines.