Gabriella Mondini is a rarity in 16th century Venice, she's a woman who practices medicine. Her father, a renowned physician, has provided her entrée to this all-male profession, and inspired in her a shared mission to understand the secrets of the human body. Then her father disappears and Gabriella faces a crisis: without her father's patronage, she is no longer permitted to treat her patients.

So she sets out across Europe to find her father. Following clues from his occasional enigmatic letters, Gabriella crosses Switzerland, Germany and France, entering strange and forbidding cities. She travels to Scotland, the Netherlands, and finally to Morocco. In each new land, she uncovers details of her father's unexplained flight, and opens new mysteries of her own. Not just the mysteries of ailments and treatments, but the ultimate mysteries of mortality, love, and the timeless human spirit. Filled with medical lore and sensuous, vivid details of Renaissance life, The Book of Madness and Cures is an intoxicating, unforgetable debut.