Now in its Third Edition, this reference work focuses on the physiologic mechanisms important to the practice of surgery. It smoothly integrates chapters that are contributed by high profile educators, all experts in their fields, who assist in preparing surgical residency curricula. Easy to read, organized and well illustrated, the clinical information contained therein is used only to illustrate the application of basic science as it relates to practice. A new topic to this edition is physiologic changes associated with aging. Eight additional major revisions to this edition include shock, nutrition, oncology, pulmonary, digestive, hematology, orthopaedics, and anesthesia.