Despite the increasing numbers of Hispanic-Serving Institutions (HSIs) and their importance in serving students who have historically been underserved in higher education, limited research has addressed the meaning of the growth of these institutions and its implications for higher education. Hispanic-Serving Institutions fills a critical gap in understanding the organizational behavior of institutions that serve large numbers of low-income, first-generation, and Latina/o students. Leading scholars on HSIs contribute chapters to this volume, exploring a wide array of topics, data sources, conceptual frameworks, and methodologies to examine HSIs’ institutional environments and organizational behavior. This cutting-edge volume explores how institutions can better serve their students and illustrates HSIs’ changing organizational dynamics, potentials, and contributions to American higher education.