The exponentially increasing amounts of biological data along with comparable
advances in computing power are making possible the construction of quantitative,
predictive biological systems models. This development could revolutionize those
biology-based fields of science. To assist this transformation, the U.S. Department of
Energy asked the National Research Council to recommend mathematical research
activities to enable more effective use of the large amounts of existing genomic
information and the structural and functional genomic information being created.
The resulting study is a broad, scientifically based view of the opportunities lying at
the mathematical science and biology interface. The book provides a review of past
successes, an examination of opportunities at the various levels of biological systems—
from molecules to ecosystems—an analysis of cross-cutting themes, and a
set of recommendations to advance the mathematics-biology connection that are
applicable to all agencies funding research in this area.Table of Contents
Front Matter
Executive Summary
1 The Nature of the Field
2 Historical Successes
3 Understanding Molecules
4 Understanding Cells
5 Understanding Organisms
6 Understanding Populations
7 Understanding Communities and Ecosystems
8 Crosscutting Themes