CONTENTS Participants Welcoming Remarks Chairman's Introduction Amniocentesis: Techniques and Complications Practical Aspects of Early Diagnosis An Overview of Problems Arising from Amniocentesis Identification of the Defective Patient: Biochemical Techniques Massachusetts Metabolic Disorders Screening Program Cytogenetic Problems in Antenatal Diagnosis Screening for Inherited Traits: Perspectives Detection of Heterozygotes Risks in Amniocentesis Use of Amniotic Fluid and Reliability of Diagnostic Procedures Control Studies in the Antenatal Diagnosis of Human Genetic-Metabolic Disorders Counseling in Genetics Administration and Ethics The Law and the Unborn Child: A Brief Review of Emerging Problems Ethical Issues Resulting from Prenatal Diagnosis