This authoritative reference published under the auspices of the American Society of Critical Care Anesthesiologists (ASCCA) is now in its Second Edition. More than 100 internationally recognized experts present state-of-the-art strategies for successful, cost-effective perioperative care and management of acutely ill patients.This thoroughly revised edition features many distinguished new contributors from anesthesiology, critical care medicine, internal medicine, surgery, and pediatrics. Timely new chapters cover medical informatics, evidence-based medicine, human genomics, research in critical care medicine, and imaging in the ICU. Chapters on acute respiratory distress syndrome, sepsis, and other diseases have been rewritten to reflect recent technological and therapeutic breakthroughs.