A mysterious disease sweeps across America, rendering men impotent, and it affects almost the entire population. It arouses fears that it will spell the end of the American nation, and even, if it travels around the world, of the human race.. A medical scientist struggling to find a cure gets involved in no-holds-barred competition among scientific institutes. A newspaper reporter following the story is one of the few men not affected, and he finds himself s a unique object of desire among women. The situation puts a question mark over the meaning of relationships, sex and love. Comedy and drama ensue, as both men find themselves involved in intrigue, skulduggery and scientific and sexual politics.