Revised to incorporate the latest advances in the neurosciences and clinical neurology, the Sixth Edition of Dr. Menkes' classic text provides a thorough understanding of all diseases affecting the developing nervous system. In clinically relevant terms, the book explains how recent developments in molecular biology, genetics, neurochemistry, neurophysiology, and neuropathology impact on the diagnosis, treatment, and care of patients. Each chapter focuses on a specific disorder or group of disorders and emphasizes differential diagnosis, disease course, treatment, and prognosis.This edition is coedited by Harvey B. Sarnat, MD, a leading expert in neuroembryology, muscle diseases, and neonatal neurology. The list of contributors has been enlarged and includes experts in infectious diseases, cytogenetics, neuroimaging, neuroimmunology, and neuro-oncology.