Well-known for its authoritative and comprehensive coverage, complete treatment of pediatric pathophysiology, and the most extensive illustration program in its field, this textbook features expert content on everything from the general principles of pathophysiology to detailed discussions of genetics and specific diseases. Chapters on alteration present the pathophysiology, clinical manifestations, and evaluation and treatment of each disease to help you learn to identify normal anatomy and physiology, as well as alterations of function in adults and in children.



Over 1,200 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes - more than in any other pathophysiology text.
A fully updated glossary includes 1,000 terms, and makes lookup easier by grouping together similar topics and terms.
Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition.
Chapter summary reviews provide concise synopses of the main points of each chapter.
Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment.
Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content.
Algorithms and flowcharts of diseases and disorders make it easy to follow the sequential progression of disease processes.
Nutrition and Disease boxes explain the link between concepts of health promotion and disease.






EXTENSIVELY Updated content reflects advances in pathophysiology including tumor biology invasion and metastases, the epidemiology of cancer, diabetes mellitus, insulin resistance, thyroid and adrenal gland disorders, female reproductive disorders including benign breast diseases and breast cancer, and a separate chapter on male reproductive disorders and cancer.
NEW! Chapter on epigenetics and disease.
Additional What's New boxes highlight the most current research and clinical development.