Like modern-day New York City, the ancient city of Teotihuacan in Central Mexico was built by a flood of immigrants who created a complex and diverse urban landscape. This detailed volume analyzes 116 burials in Teopancazco, a powerful neighborhood that controlled most of the city’s intake and distribution of foreign raw materials. Applying sophisticated bioarchaeological techniques such as isotope analysis, trace elements, and DNA profiling, this holistic study gives life to the population of the earliest known multiethnic metropolis.