This volume contains the proceedings of the Tenth International Conference on Domain Decomposition Methods, which focused on the latest developments in realistic applications in structural mechanics, structural dynamics, computational fluid dynamics, and heat transfer. The proceedings of these conferences have become standard references in the field and contain seminal papers as well as the latest theoretical results and reports on practical applications.This volume is divided into four parts: the first part contains invited papers (some of which survey developments over the past decade), and the other parts gather material from minisymposia and contributed presentations under three headings: Algorithms, Theory, and Applications. The electronic version is available at no additional charge to purchasers of the print volume. Access instructions are provided in the book. There is also the option to purchase only the electronic version.