By the end of the twentieth century, Adrian C. Louis had become one of the most powerful voices in the canon of Native American literature. His poetry and fiction have been widely read, anthologized, and translated. Skins, first published in 1995, is now introduced with a new foreword by David Pichaske, professor of English at Southwest Minnesota State University, and Louis's personal friend and colleague.

It's the early 1990s and Rudy Yellow Shirt and his brother, Mogie, are living on the Pine Ridge Reservation in South Dakota, home of the legendary Oglala Sioux warrior Crazy Horse. Both Vietnam veterans, the men struggle with daily life on "the rez." Rudy, a criminal investigator with the Pine Ridge Public Safety Department, frequently arrests his neighbors and friends, including his brother, who has become a rez wino.

But when Rudy falls and hits his head on a rock while pursuing a suspected murderer, Iktome the trickster enters his brain.Iktome restores Rudy's youthful sexual vigor—long-lost to years of taking high blood pressure pills—and ignites his desire for political revenge via an alter ego, the "Avenging Warrior." In a violent act, the Avenging Warrior torches the local liquor store, nearly burning Mogie alive while he is hiding on the store's roof, plotting to steal booze. Although the brothers reconcile before Mogie dies, he gives the Avenging Warrior one final mission: go to Mount Rushmore and blow the nose off George Washington's granite face.

In 2002, Skins made into a movie directed by Chris Eyre.