This is an open access book. This event is co-organized by the Institute of Science Innovation and Culture (ISIC) and Research and Development Institute (RDI), Rajamangala University of Technology Krungthep, Thailand. This year’s ICEHUM 2022 was held online and onsite on 26  November 2022. The theme of this conference is “Leading and Being Sustainable in the COVID-19 New Normal“. This conference aspires to bring to light new standards, models, and reference guides that will help humanity rise above the challenges of COVID-19, leading men and women to embrace the new normal, no longer uncertain but living a sustainable existence.