This unique collection of 55 multidisciplinary case studies enables students to better integrate material from all the major clinical laboratory disciplines—Blood Bank, Chemistry, Hematology, Immunology, Microbiology, Urinalysis—by giving them the opportunity to “experience” how departments work together to help the physician make a diagnosis and determine the best course of treatment for the patient. Unlike traditional case studies that are based solely on the medical model (with patient history followed by questions leading to the diagnosis), these cases not only correlate results with disease states, but serve as problem-solving and critical-thinking exercises based on real scenarios that occur in typical clinical laboratories. Pathophysiology, etiology and epidemiology are naturally reviewed as a case unfolds, and students deal firsthand with interpreting data from two, three or four disciplines, challenging them to integrate laboratory data from different departments and to think critically about what they mean.