The Molecules Annual summarizes the papers published in 1996 in Molecules on the Internet. All electronic features are included on the CD-ROM. Molecules is a journal of synthetic organic and natural product chemistry. It covers mainly small- and medium-sized molecules, their preparation (synthesis, biosynthesis, extraction, etc.), structural elucidation (X-ray crystallography, NMR, etc.) their properties (chemical and biological activities) and applications (functional materials, additives, catalysts, etc.). Also covered: combinatorial synthesis, engineering and robotics of multi-step synthesis and natural product isolation, applications of compound collections, molecular diversity assessments, compound archives management, and compound database design and management.