This issue of MRI Clinics of North America focuses on Breast Cancer, and is edited by Dr. Jessica Leung. Articles will include: Breast MRI: Atlas of anatomy, physiology, pathophysiology, and BI-RADS lexicon; Neoadjuvant therapy monitoring, including inflammatory breast cancer; Breast MRI biopsy considerations: Technique, histologic upgrading, and radiologic-pathologic concordance; Breast MRI techniques and developments: 1.5 vs 3T, diffusion, fast MRI, PET-MRI, and other developing techniques; ACR Accreditation, Performance Metrics, Reimbursement, and Economic Considerations in Breast MRI; Screening: high-risk and dense breasts, especially compared with tomosynthesis and ultrasound; Extent of breast disease, especially compared with tomosynthesis and ultrasound, with special focus on nodal assessment; Problem-solving tool for imaging finding and clinical symptoms of breast cancer; MRI compared with contrast-enhanced mammography; MRI compared with molecular breast imaging; MRI compared with positron emission mammography; How does MRI help care for my breast cancer patient? Perspective of a surgical oncologist; How does MRI help care for my breast cancer patient? Perspective of a medical oncologist; How does MRI help care for my breast cancer patient? Perspective of a radiation oncologist; and more!