This completely updated Sixth Edition comprehensive review now includes a CD-ROM. Already rated as a top study tool, the authors have made several revisions to deliver the most valuable content and style available on the market for preparation of the USMLE Step 1. The new Introductory section reflects the current computerized USMLE Step 1 format, the text is divided into 50-question tests, and also features clinical vignettes as implemented on the USMLE. Additional features include more clinically oriented illustrations, such as MRIs and CTs, and color plates in multiple signatures as seen on the exam.