In this bold, provocative account, the author argues that the phenomena of life and mind elude purely materialistic explanations. Living matter occupies a unique phase of existence which results from the complex transformation of its biochemical synergies. Analogous phase changes account for mind and self-reflexive consciousness. A central role in the living state is played by intelligence, which has not been recognised as a non-negotiable precondition of organic existence. Yet the concept of evolutionary adaptivity relies tacitly on it. Thus the book amounts to a serious challenge to the overly theoretical paradigmata of the last half-century with their timorous evasion of biological fundamentals. However, although the work relies on up-to-date research of the life sciences, it is a primarily philosophical enquiry, dealing head on with many unsolved problems of life and mind, and culminating in a detailed “ontological proof” of the mind system.