The year is 2075, and the vast majority of humanity is dead. The global outbreak of a new strain of virus wiped out over 99% of the population. The lone hope rests on the slim, unready shoulders of Dr. Justin Kaes and a small team of specialists from the Center for Disease Control. The researchers have discovered a cure for the plague in the blood of a cantankerous 102 year old. But there's one minor problem: the old man couldn't care less whether humanity lives or dies. And he most certainly doesn't feel like going on a road trip to sunny California. On the way to the coast lie murderous tribes, cults, voracious animals, and the toxic remains of civilization. They face a world gone backwards, technology and industry reduced to rusting garbage. Their mission seems doomed...But there are a few decent souls still out there, citizens of Plaguesville, USA.