Seeking to unite the history of science and urban history, this book emphasizes the active role cities play in shaping both scientific practice and scientific knowledge. Furthermore, the authors argue that cities themselves have to be viewed as mediated by science. Four interconnections of science and the city are discussed: the relationship between scientific expertise and urban politics; science's role in the cultural representation of the city; the embedment of scientific activity in the city's social and material infrastructure; and the interaction between science and everyday urban life.