The book titled “Microbiome and Plant Nutrition꞉ A Roadmap Towards Sustainable Agriculture” is expected to direct many emerging research pathways needed at local and global levels for sustainable agricultural package and practices. This volume incorporates thirteen seminal chapters on issue based research and their practical applications covering latest information and progress in different areas of microbial supplemented crop nutrition for sustainable agriculture. The book highlights the frontier issues and applications of plant‑microbe interaction in crop nutritional strategy with topics like System biology of plant microbe interaction, Plant growth‑promoting rhizobacteria꞉ a context for sustainable agriculture, Plant growth‑promoting endophytes꞉ a context for sustainable agriculture, The role of the mycorrhiza in nutrient uptake, Plant nitrogen, phosphorus and sulphur nutrition꞉ a microbial perspective, Carbon and nitrogen turnover in soils and plant rhizo‑deposition, Root exudates꞉ a link to plant‑microbe nutritional interactions and insight into the metabolic and nutrition network pathway of plant‑microbe interaction, Commercialization perspective of bio‑stimulants for sustainable agriculture, Interconnection of plants with microbiomes in changing climate꞉ a functional extension of the host and heavy metal dynamics in rice soil꞉ an alleviation through microbial intervention approach. This book will be very useful for the scholars, biotechnologists, agricultural scientists, plant nutritionists, researchers, teachers and students in the emerging field of soil‑microbiome and plant nutrition dynamics in the resilient climatic agriculture era.