This work brings together over 30 contributors with expertise in a variety of disciplines related to the topic. Although efforts continue toward reduction or elimination of pesticide chemicals in the management of pests in agriculture, public health and the urban arena, chemicals will continue to be one of the main weapons in control of insects, weeds, nematodes, weeds and so on for some time to come. While considerable information is known about the acute toxicity of these compounds, information on the chronic effects from exposure to minute amounts of pesticide residues in food, water, air and soil is limited. This work approaches the topic from several angles, including pesticide epidemiology, new modes of action to minimize non-target exposure, bioremediation of contaminated areas, molecular biology of the modes of action of detoxication of pesticides, and the dynamics of pesticide movement in the environment.