This volume considers regional approaches to social complexity from a variety of perspectives and at a global scale. John F. Cherry has been a key figure in regional-scale inquiry and broader disciplinary interfaces throughout his career, producing, mentoring, and inspiring a remarkably diverse body of work, which nevertheless remains oriented around this central theme. While Cherry’s work is the inspiration for this volume and the papers within it, this should not be seen as a traditional festschrift, or piecemeal homage to the honorand’s career. Rather, it aims to explore this core concern of regional approaches to society and complexity in comparative perspective, first in the Aegean, then branching out to the wider Mediterranean, New World, and finally reflecting on relevant issues of concern to all archaeologists working at levels above the site.