This book lays out a systematic approach to comparative case analysis based on fundamental insights of information theory. This unique approach helps students, policymakers, professionals, and scholars learn more from the information they have and exercise better judgment under conditions of uncertainty. Techniques presented are conceptually intuitive, straightforward, and require minimal quantitative skills. The approach avoids the limitations of traditional statistics in the small-n context and allows analysts to systematically assess and compare the impact of a set of factors on case outcomes with easy-to-use analytics.