Although best known the world over for his masterpiece novel, Don Quixote de la Mancha, published in two parts in 1605 and 1615, the antics of the would-be knight-errant and his simple squire only represent a fraction of the trials and tribulations, both in the literary world and in society at large, of this complex man. Poet, playwright, soldier, slave, satirist, novelist, political commentator, and literary outsider, Cervantes achieved a minor miracle by becoming one of the rarest of things in the Early-Modern world of letters: an international best-seller during his lifetime, with his great novel being translated into multiple languages before his death in 1616. The principal objective of The Oxford Handbook of Cervantes is to create a resource in English that provides a fully comprehensive overview of the life, works, and influences of Miguel de Cervantes Saavedra (1547-1616). This volume contains seven sections, exploring in depth Cervantes's life and how the trials, tribulations, and hardships endured influenced his writing. Cervantistas from numerous countries, including the United Kingdom, Spain, Ireland, the United States, Canada, and France offer their expertise with the most up-to-date research and interpretations to complete this wide-ranging, but detailed, compendium of a writer not known for much other than his famous novel outside of the Spanish-speaking world. Here we explore his famous novelDon Quixote de la Mancha, his other prose works, his theatrical output, his poetry, his sources, influences, and contemporaries, and finally reception of his works over the last four hundred years.