After two centuries of nation-building, the world has entered an era of region-building in search of political stability, cultural cohesion, and socio-economic development. Nations involved in the regional structures and integration schemes that are emerging in most regions of the world are deepening their ambitions, with Europe’s integration experience often used as an experimental template or theoretical model. Volume I provides a political-analytical framework for recognizing the central role of the European Union not only as a conceptual model but also a normative engine in the global proliferation of regional integration. It also gives a comprehensive treatment of the focus, motives, and objectives of non-European integration efforts. Volume II offers a unique collection of documents that give the best available overview of the legal and political evolution of region-building based on official documents and stated objectives of the relevant regional groupings across all continents. Together, these volumes are important contributions for understanding the evolution of global affairs in an age when power shifts provide new challenges and opportunities for transatlantic partners and the world community.