The lives and practices of 100 healers and spiritual leaders from a variety of North American Native peoples are described here. Included are both historical and contemporary figures. While some of the figures are well known, such as the Apache Goyathlay (Geronimo), others are more obscure. This book is one of the few available sources of detailed information on their lives and careers.

Entries include a summary of the individual's life, a history of the person's early life, a description of the highlights of his or her career as a healer or spiritual practitioner, and recommendations for further reading. Photos of the individuals illustrate 26 of the entries. A bibliography, subject index, and two appendixes that list individuals by birth date and by Nation or group round out the volume.