Laboratory Manual for General Chemistry: Atoms First, Second Edition is organized using the atoms first approach and is written to correspond with the Second Edition of General Chemistry: Atoms First by McMurry/Fay. This manual contains twenty-four experiments with a focus on real world applications, following an intuitive logic progressing from the simplest building blocks to successively more complex concepts.

Each experiment covers one or more topics discussed within a chapter of the textbook to help students understand the underlying concepts covered in the lecture course. Additionally, each experiment contains a set of pre-laboratory questions (also assignable in MasteringChemistry^®), an introduction, a background section explaining concepts that each student is expected to master for a full understanding of the experimental results,  a step-by-step procedure (including safety information), and a report section featuring post-laboratory questions.