This book is a collection of extended papers presented at the Cyber Physical, Computer and Automation System (CPCAS 2019), Bali – Indonesia, 13–15 November 2019. The book includes chapters in three prime areas: (1) autonomous systems and controls; (2) human–machine interaction and human-related engineering; and (3) interconnected things. Autonomous systems and controls are systems of engineering that work with or without human intervention. Human–machine interaction involves sensor and actuator technology to detect human behavior, intentions, and decisions and also to provide the ability of a machine to interact with humans to achieve the expected performance. Interconnected things consist of a network of computer-controlled physical mechanisms communicating with each other for efficient operation and improving system capabilities.