This book reviews air pollutants and their effects on human health, biodiversity, and environmental quality in the context of the One Health framework. Written by experts in the field, the book covers topics such as natural and anthropogenic sources of air pollutants, air pollutants classification based on their chemical composition, physical properties, and origins, and consequences of air pollution on ecosystems, wildlife, and human communities. In this book, readers will find a detailed examination of pollutants, such as particulate matter, volatile organic compounds, and greenhouse gases, and will learn about the mechanisms by which pollutants impact, for instance, the respiratory, cardiovascular, and neurological systems. The book highlights the need for understanding the different pollutants and their One Health effects as a foundation for developing effective regulations, emission controls, cleaner technologies, and promoting lifestyle changes. The book also offers a global perspective on air pollution, and discusses the disproportionate impacts of air pollution on vulnerable populations. In alignment with the United Nations Sustainable Development Goals (SDG), specifically SDG 3 (Good Health and Well-being), SDG 7 (Affordable and Clean Energy), and SDG 11 (Sustainable Cities and Communities), this book takes a focused approach to the One Health implications of various air pollutants and is an important contribution to the global effort to mitigate the impact of air pollution on human health, biodiversity security, and environmental quality. Together with its companion work “Sustainable Strategies for Air Pollution Mitigation”, this book is a valuable resource for students, researchers, policymakers, and anyone seeking a comprehensive perspective on this critical environmental and public health challenge.