A comprehensive guide to the factors involved in the aetiology of autoimmune diseases in general, and of Sjoegren's syndrome in particular. The book reflects the cutting edge of research and focuses on advances made by the application of molecular biological techniques. A wide range of topics are covered, including advances in serological assessment and therapy, links between autoimmunity and malignancy, animal models of Sjoegren's syndrome, and the role of the T-cell receptor and cell adhesion molecules.