Designer Vaccines: Principles for Successful Prophylaxis seeks answers to these important questions and explores how immunological knowledge can be applied in the formulation and delivery of vaccines. Instead of focusing on the rating of existing vaccines, this forward-thinking text looks to how new vaccines can be developed and existing ones improved upon. The book provides sound immunological theory and fact as a basis for solving vaccine design problems.
Beginning with a discussion of disease and immunity to infection, Designer Vaccines: Principles for Successful Prophylaxis describes how events leading to immunity following infection must be considered in the rational design of vaccines. It also introduces the mucosal immune system and considers the special requirements of oral vaccines. Both viral and bacterial vectors for vaccine delivery are reviewed in detail.

Contributions by: Michael E. G. Boursnell, Yang Liu, Nicholas A. Mitchison, Brigitte Muller, David W. Pascual, Hiroshi Kiyono, Jerry R. McGhee, Kevin F. Jones, Mike Sheppard, D. Mark Estes