This completely revised textbook helps students integrate the broad range of contemporary drug therapy with the management of disease. It enables students to apply the basics of therapeutics to clinical situations. New to this edition are: expanded coverage of pathophysiology disease; two new sections that cover the psychological and social aspects of diseases; Treatment Goals and Key Points sections at the end of each chapter; and a new drug index provided before the general index. Also included are four new chapters on Alcohol Abuse and Cystic Fibrosis, MCV-Smoking Cessation, Infectious Disease Introduction, and Supportive Care Therapies for the Cancer Patient.