This book presents the peer-reviewed proceedings of the 4th International Conference on Advanced Machine Learning Technologies and Applications (AMLTA 2019), held in Cairo, Egypt, on March 28–30, 2019, and organized by the Scientific Research Group in Egypt (SRGE). The papers cover the latest research on machine learning, deep learning, biomedical engineering, control and chaotic systems, text mining, summarization and language identification, machine learning in image processing, renewable energy, cyber security, and intelligence swarms and optimization.