Now in its second edition, this collection explores how multiple health determinants, such as colonialism, gender, culture, early childhood development, the environment, geography, HIV/AIDS, medicine, and policy, impact the health status of Indigenous peoples in Canada. Grounded in expert voices of First Nations, Inuit, and Métis writers from coast to coast, this updated edition includes a chapter on environment and land defense; a foreword written by Dr. Evan Adams, Chief Medical Officer of the First Nations Health Authority; chapters by Liz Howard and Helen Knott, Indigenous poets; and an updated arrangement that reflects the significant social and political events that dominated headlines over the last two years, such as the protests at Standing Rock, North Dakota, the US national election of 2016, the Indigenous youth suicide epidemic, and the enquiry into murdered and missing Indigenous women and girls in Canada. This revolutionary book is appropriate for undergraduate and graduate students enrolled in courses on health, public and population health, community health sciences, medicine, nursing, and social work.