This book is centered on the two minicourses conducted by C Liverani (Rome) and J Sjoestrand (Paris) on the return to equilibrium in classical statistical mechanics and the location of quantum resonances via semiclassical analysis, respectively. The other contributions cover related topics of classical and quantum mechanics, such as scattering theory, classical and quantum statistical mechanics, dynamical localization, quantum chaos, ergodic theory and KAM techniques.