Following 50 years of glucocorticoid use in a clinical setting, an
international body of expert scientists and physicians presents the most
expansive survey of glucocorticoid pharmacology to date. This work
traces the history of glucocorticoid biology from the seminal
description of glucocorticoid insufficiency by Thomas Addison in the
mid-19th century, up to current advances in elucidating the molecular
basis of glucocorticoid action. Important discoveries are presented, as
well as milestones in drug development, a survey of current clinical
practice, and prospects for novel glucocorticoid-based therapeutics.
Scientists and clinicians will appreciate the scope of this work, which
is of special interest to workers in the fields of endocrinology,
inflammation and autoimmune disease.